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Serum zinc level is associated with liver dysfunction caused by white smoke inhalation

BACKGROUND: White smoke bomb exposure in the military setting could result in organ injuries, which is uncommon and has been rarely described in previous studies. The aim of this study is to observe whether serum zinc levels are associated with liver function after white smoke inhalation. METHODS: F...

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Autores principales: Xie, Fei, Xie, Lixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225814/
https://www.ncbi.nlm.nih.gov/pubmed/30430020
http://dx.doi.org/10.1093/gastro/goy008
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author Xie, Fei
Xie, Lixin
author_facet Xie, Fei
Xie, Lixin
author_sort Xie, Fei
collection PubMed
description BACKGROUND: White smoke bomb exposure in the military setting could result in organ injuries, which is uncommon and has been rarely described in previous studies. The aim of this study is to observe whether serum zinc levels are associated with liver function after white smoke inhalation. METHODS: Fifteen patients with white smoke exposure were the subjects in this study. The clinical manifestations, liver function tests and the serum zinc levels were analysed. RESULTS: The level of serum zinc was increased in the moderate or severe group (n = 4) compared with that in the mild group (n = 11). The four cases in the moderate or severe group had delayed impairment of liver function with an elevation of alanine transaminase. Additionally, increased blood concentrations of hyaluronic acid were found in three patients in the moderate or severe group. But no hexachloroethane or trichloropropane was detected. CONCLUSION: This study suggested that serum zinc levels may be associated with the severity of liver injuries after white smoke inhalation.
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spelling pubmed-62258142018-11-14 Serum zinc level is associated with liver dysfunction caused by white smoke inhalation Xie, Fei Xie, Lixin Gastroenterol Rep (Oxf) Original Articles BACKGROUND: White smoke bomb exposure in the military setting could result in organ injuries, which is uncommon and has been rarely described in previous studies. The aim of this study is to observe whether serum zinc levels are associated with liver function after white smoke inhalation. METHODS: Fifteen patients with white smoke exposure were the subjects in this study. The clinical manifestations, liver function tests and the serum zinc levels were analysed. RESULTS: The level of serum zinc was increased in the moderate or severe group (n = 4) compared with that in the mild group (n = 11). The four cases in the moderate or severe group had delayed impairment of liver function with an elevation of alanine transaminase. Additionally, increased blood concentrations of hyaluronic acid were found in three patients in the moderate or severe group. But no hexachloroethane or trichloropropane was detected. CONCLUSION: This study suggested that serum zinc levels may be associated with the severity of liver injuries after white smoke inhalation. Oxford University Press 2018-11 2018-03-07 /pmc/articles/PMC6225814/ /pubmed/30430020 http://dx.doi.org/10.1093/gastro/goy008 Text en © The Author(s) 2018. Published by Oxford University Press and Sixth Affiliated Hospital of Sun Yat-Sen University http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Original Articles
Xie, Fei
Xie, Lixin
Serum zinc level is associated with liver dysfunction caused by white smoke inhalation
title Serum zinc level is associated with liver dysfunction caused by white smoke inhalation
title_full Serum zinc level is associated with liver dysfunction caused by white smoke inhalation
title_fullStr Serum zinc level is associated with liver dysfunction caused by white smoke inhalation
title_full_unstemmed Serum zinc level is associated with liver dysfunction caused by white smoke inhalation
title_short Serum zinc level is associated with liver dysfunction caused by white smoke inhalation
title_sort serum zinc level is associated with liver dysfunction caused by white smoke inhalation
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225814/
https://www.ncbi.nlm.nih.gov/pubmed/30430020
http://dx.doi.org/10.1093/gastro/goy008
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