Management of chronic hepatitis B during pregnancy

Chronic hepatitis B is globally prevalent and is a major cause of cirrhosis and hepatocellular carcinoma. Despite immunoprophylaxis against hepatitis B in pregnancy, perinatal transmission still occurs in at least 10% of the children born to a mother with high level of viremia. Decisions regarding h...

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Detalles Bibliográficos
Autores principales: Aslam, Aysha, Campoverde Reyes, Karen Joanie, Malladi, Vijayram Reddy, Ishtiaq, Rizwan, Lau, Daryl T Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Review Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225824/
https://www.ncbi.nlm.nih.gov/pubmed/30430013
http://dx.doi.org/10.1093/gastro/goy025
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author Aslam, Aysha
Campoverde Reyes, Karen Joanie
Malladi, Vijayram Reddy
Ishtiaq, Rizwan
Lau, Daryl T Y
author_facet Aslam, Aysha
Campoverde Reyes, Karen Joanie
Malladi, Vijayram Reddy
Ishtiaq, Rizwan
Lau, Daryl T Y
author_sort Aslam, Aysha
collection PubMed
description Chronic hepatitis B is globally prevalent and is a major cause of cirrhosis and hepatocellular carcinoma. Despite immunoprophylaxis against hepatitis B in pregnancy, perinatal transmission still occurs in at least 10% of the children born to a mother with high level of viremia. Decisions regarding hepatitis B therapy during pregnancy must take into account the benefits and safety for both the mother and the unborn baby. In this review, we summarize the current treatment options for chronic hepatitis B with a focus on management during pregnancy and the evidence-based strategies to prevent vertical transmission of hepatitis B virus (HBV).
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spelling pubmed-62258242018-11-14 Management of chronic hepatitis B during pregnancy Aslam, Aysha Campoverde Reyes, Karen Joanie Malladi, Vijayram Reddy Ishtiaq, Rizwan Lau, Daryl T Y Gastroenterol Rep (Oxf) Review Articles Chronic hepatitis B is globally prevalent and is a major cause of cirrhosis and hepatocellular carcinoma. Despite immunoprophylaxis against hepatitis B in pregnancy, perinatal transmission still occurs in at least 10% of the children born to a mother with high level of viremia. Decisions regarding hepatitis B therapy during pregnancy must take into account the benefits and safety for both the mother and the unborn baby. In this review, we summarize the current treatment options for chronic hepatitis B with a focus on management during pregnancy and the evidence-based strategies to prevent vertical transmission of hepatitis B virus (HBV). Oxford University Press 2018-11 2018-07-24 /pmc/articles/PMC6225824/ /pubmed/30430013 http://dx.doi.org/10.1093/gastro/goy025 Text en © The Author(s) 2018. Published by Oxford University Press and Sixth Affiliated Hospital of Sun Yat-Sen University http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Review Articles
Aslam, Aysha
Campoverde Reyes, Karen Joanie
Malladi, Vijayram Reddy
Ishtiaq, Rizwan
Lau, Daryl T Y
Management of chronic hepatitis B during pregnancy
title Management of chronic hepatitis B during pregnancy
title_full Management of chronic hepatitis B during pregnancy
title_fullStr Management of chronic hepatitis B during pregnancy
title_full_unstemmed Management of chronic hepatitis B during pregnancy
title_short Management of chronic hepatitis B during pregnancy
title_sort management of chronic hepatitis b during pregnancy
topic Review Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225824/
https://www.ncbi.nlm.nih.gov/pubmed/30430013
http://dx.doi.org/10.1093/gastro/goy025
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