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Epigenetic regulation of HOTAIR in advanced chronic myeloid leukemia

PURPOSE: Chronic myeloid leukemia (CML) accounts for ~10% of leukemia cases, and its progression involves epigenetic gene regulation. This study investigated epigenetic regulation of HOTAIR and its target microRNA, miR-143, in advanced CML. PATIENTS AND METHODS: We first isolated bone marrow mononuc...

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Detalles Bibliográficos
Autores principales: Li, Ziye, Luo, Jianmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225916/
https://www.ncbi.nlm.nih.gov/pubmed/30464631
http://dx.doi.org/10.2147/CMAR.S166859

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