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Personalized identification of tumor-associated immunogenic neoepitopes in hepatocellular carcinoma in complete remission after sorafenib treatment
Sorafenib, a multi-targeted kinase inhibitor, is the current standard systemic treatment for advanced hepatocellular carcinoma. Sorafenib has anti-angiogenic and anti-proliferative properties and is also known to favor anti-tumor T cell responses by reducing the population of immunosuppressive cells...
Autores principales: | Vrecko, Sindy, Guenat, David, Mercier-Letondal, Patricia, Faucheu, Hugues, Dosset, Magalie, Royer, Bernard, Galaine, Jeanne, Boidot, Romain, Kim, Stefano, Jary, Marine, Adotévi, Olivier, Borg, Christophe, Godet, Yann |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226040/ https://www.ncbi.nlm.nih.gov/pubmed/30459932 http://dx.doi.org/10.18632/oncotarget.26247 |
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