Predicting bioprocess targets of chemical compounds through integration of chemical-genetic and genetic interactions

Chemical-genetic interactions–observed when the treatment of mutant cells with chemical compounds reveals unexpected phenotypes–contain rich functional information linking compounds to their cellular modes of action. To systematically identify these interactions, an array of mutants is challenged wi...

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Detalles Bibliográficos
Autores principales: Simpkins, Scott W., Nelson, Justin, Deshpande, Raamesh, Li, Sheena C., Piotrowski, Jeff S., Wilson, Erin H., Gebre, Abraham A., Safizadeh, Hamid, Okamoto, Reika, Yoshimura, Mami, Costanzo, Michael, Yashiroda, Yoko, Ohya, Yoshikazu, Osada, Hiroyuki, Yoshida, Minoru, Boone, Charles, Myers, Chad L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226211/
https://www.ncbi.nlm.nih.gov/pubmed/30376562
http://dx.doi.org/10.1371/journal.pcbi.1006532

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