INAVA-ARNO complexes bridge mucosal barrier function with inflammatory signaling

Homeostasis at mucosal surfaces requires cross-talk between the environment and barrier epithelial cells. Disruption of barrier function typifies mucosal disease. Here we elucidate a bifunctional role in coordinating this cross-talk for the inflammatory bowel disease risk-gene INAVA. Both activities...

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Detalles Bibliográficos
Autores principales: Luong, Phi, Hedl, Matija, Yan, Jie, Zuo, Tao, Fu, Tian-Min, Jiang, Xiaomo, Thiagarajah, Jay R, Hansen, Steen H, Lesser, Cammie F, Wu, Hao, Abraham, Clara, Lencer, Wayne I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226287/
https://www.ncbi.nlm.nih.gov/pubmed/30355448
http://dx.doi.org/10.7554/eLife.38539

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