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Functional analysis of potential cleavage sites in the MERS-coronavirus spike protein
The Middle East respiratory syndrome-related coronavirus (MERS-CoV) can cause severe disease and has pandemic potential. Therefore, development of antiviral strategies is an important task. The activation of the viral spike protein (S) by host cell proteases is essential for viral infectivity and th...
Autores principales: | Kleine-Weber, Hannah, Elzayat, Mahmoud Tarek, Hoffmann, Markus, Pöhlmann, Stefan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226446/ https://www.ncbi.nlm.nih.gov/pubmed/30413791 http://dx.doi.org/10.1038/s41598-018-34859-w |
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