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Structure analysis and antiviral activity of CW-33 analogues against Japanese encephalitis virus
Japanese encephalitis virus (JEV) is a member of neurotropic flaviviruses transmitted by mosquito bites, causing severe central nervous system disorders. Current JEV genotype III vaccines have a low protection against genotype I isolates in the risk zone. The lead compound CW-33, ethyl 2-(3′,5′-dime...
Autores principales: | Lien, Jin-Cherng, Wang, Ching-Ying, Lai, Hsueh–Chou, Lu, Chien-Yi, Lin, Yu-Fong, Gao, Ging-Yan, Chen, Kuan-Chung, Huang, An-Cheng, Huang, Su-Hua, Lin, Cheng-Wen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226475/ https://www.ncbi.nlm.nih.gov/pubmed/30413749 http://dx.doi.org/10.1038/s41598-018-34932-4 |
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