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Structure analysis and antiviral activity of CW-33 analogues against Japanese encephalitis virus

Japanese encephalitis virus (JEV) is a member of neurotropic flaviviruses transmitted by mosquito bites, causing severe central nervous system disorders. Current JEV genotype III vaccines have a low protection against genotype I isolates in the risk zone. The lead compound CW-33, ethyl 2-(3′,5′-dime...

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Detalles Bibliográficos
Autores principales: Lien, Jin-Cherng, Wang, Ching-Ying, Lai, Hsueh–Chou, Lu, Chien-Yi, Lin, Yu-Fong, Gao, Ging-Yan, Chen, Kuan-Chung, Huang, An-Cheng, Huang, Su-Hua, Lin, Cheng-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226475/
https://www.ncbi.nlm.nih.gov/pubmed/30413749
http://dx.doi.org/10.1038/s41598-018-34932-4

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