Fibroblast growth factor-2, but not the adipose tissue-derived stromal cells secretome, inhibits TGF-β1-induced differentiation of human cardiac fibroblasts into myofibroblasts

Transforming growth factor-β1 (TGF-β1) is a potent inducer of fibroblast to myofibroblast differentiation and contributes to the pro-fibrotic microenvironment during cardiac remodeling. Fibroblast growth factor-2 (FGF-2) is a growth factor secreted by adipose tissue-derived stromal cells (ASC) which...

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Detalles Bibliográficos
Autores principales: Liguori, Tácia Tavares Aquinas, Liguori, Gabriel Romero, Moreira, Luiz Felipe Pinho, Harmsen, Martin Conrad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226511/
https://www.ncbi.nlm.nih.gov/pubmed/30413733
http://dx.doi.org/10.1038/s41598-018-34747-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226511/
https://www.ncbi.nlm.nih.gov/pubmed/30413733
http://dx.doi.org/10.1038/s41598-018-34747-3

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