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Cryptic binding sites become accessible through surface reconstruction of the type I collagen fibril
Collagen fibril interactions with cells and macromolecules in the extracellular matrix drive numerous cellular functions. Binding motifs for dozens of collagen-binding proteins have been determined on fully exposed collagen triple helical monomers. However, when the monomers are assembled into the f...
Autores principales: | Zhu, Jie, Hoop, Cody L., Case, David A., Baum, Jean |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226522/ https://www.ncbi.nlm.nih.gov/pubmed/30413772 http://dx.doi.org/10.1038/s41598-018-34616-z |
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