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Perinatal insults and neurodevelopmental disorders may impact Huntington's disease age of diagnosis

INTRODUCTION: The age of diagnosis of Huntington's disease (HD) varies among individuals with the same HTT CAG-repeat expansion size. We investigated whether early-life events, like perinatal insults or neurodevelopmental disorders, influence the diagnosis age. METHODS: We used data from 13,856...

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Detalles Bibliográficos
Autores principales: Barkhuizen, Melinda, Rodrigues, Filipe B., Anderson, David G., Winkens, Bjorn, Wild, Edward J., Kramer, Boris W., Gavilanes, A.W.Danilo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226577/
https://www.ncbi.nlm.nih.gov/pubmed/29804730
http://dx.doi.org/10.1016/j.parkreldis.2018.05.016