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Clinical Validation of Newly Developed Multiplex Kit Using Luminex xMAP Technology for Detecting Simultaneous RAS and BRAF Mutations in Colorectal Cancer: Results of the RASKET-B Study()

Detection of RAS and BRAF mutations is essential to determine the optimal treatment strategy for metastatic colorectal cancer (CRC). We prospectively evaluated the MEBGEN RASKET-B KIT (RASKET-B), a novel multiplex kit, simultaneously detecting 48 types of RAS mutations and the BRAF V600E mutation us...

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Detalles Bibliográficos
Autores principales: Taniguchi, Hiroya, Okamoto, Wataru, Muro, Kei, Akagi, Kiwamu, Hara, Hiroki, Nishina, Tomohiro, Kajiwara, Takeshi, Denda, Tadamichi, Hironaka, Shuichi, Kudo, Toshihiro, Satoh, Taroh, Yamanaka, Takeharu, Abe, Yukiko, Fukushima, Yoshiyuki, Yoshino, Takayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226617/
https://www.ncbi.nlm.nih.gov/pubmed/30412858
http://dx.doi.org/10.1016/j.neo.2018.10.004