Cargando…

Social and Economic Burden Associated With Typhoid Fever in Kathmandu and Surrounding Areas: A Qualitative Study

Typhoid fever is a significant contributor to infectious disease mortality and morbidity in low- and middle-income countries, particularly in South Asia. With increasing antimicrobial resistance, commonly used treatments are less effective and risks increase for complications and hospitalizations. D...

Descripción completa

Detalles Bibliográficos
Autores principales: Kaljee, Linda M, Pach, Alfred, Garrett, Denise, Bajracharya, Deepak, Karki, Kshitji, Khan, Imran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226633/
https://www.ncbi.nlm.nih.gov/pubmed/28973415
http://dx.doi.org/10.1093/infdis/jix122
_version_ 1783369984923140096
author Kaljee, Linda M
Pach, Alfred
Garrett, Denise
Bajracharya, Deepak
Karki, Kshitji
Khan, Imran
author_facet Kaljee, Linda M
Pach, Alfred
Garrett, Denise
Bajracharya, Deepak
Karki, Kshitji
Khan, Imran
author_sort Kaljee, Linda M
collection PubMed
description Typhoid fever is a significant contributor to infectious disease mortality and morbidity in low- and middle-income countries, particularly in South Asia. With increasing antimicrobial resistance, commonly used treatments are less effective and risks increase for complications and hospitalizations. During an episode of typhoid fever, households experience multiple social and economic costs that are often undocumented. In the current study, qualitative interview data from Kathmandu and surrounding areas provide important insights into the challenges that affect those who contract typhoid fever and their caregivers, families, and communities, as well as insight into prevention and treatment options for health providers and outreach workers. When considering typhoid fever cases confirmed by blood culture, our data reveal delays in healthcare access, financial and time costs burden on households, and the need to increase health literacy. These data also illustrate the impact of limited laboratory diagnostic equipment and tools on healthcare providers’ abilities to distinguish typhoid fever from other febrile conditions and treatment challenges associated with antimicrobial resistance. In light of these findings, there is an urgent need to identify and implement effective preventive measures including vaccination policies and programs focused on at-risk populations and endemic regions such as Nepal.
format Online
Article
Text
id pubmed-6226633
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-62266332018-11-15 Social and Economic Burden Associated With Typhoid Fever in Kathmandu and Surrounding Areas: A Qualitative Study Kaljee, Linda M Pach, Alfred Garrett, Denise Bajracharya, Deepak Karki, Kshitji Khan, Imran J Infect Dis Supplement Articles Typhoid fever is a significant contributor to infectious disease mortality and morbidity in low- and middle-income countries, particularly in South Asia. With increasing antimicrobial resistance, commonly used treatments are less effective and risks increase for complications and hospitalizations. During an episode of typhoid fever, households experience multiple social and economic costs that are often undocumented. In the current study, qualitative interview data from Kathmandu and surrounding areas provide important insights into the challenges that affect those who contract typhoid fever and their caregivers, families, and communities, as well as insight into prevention and treatment options for health providers and outreach workers. When considering typhoid fever cases confirmed by blood culture, our data reveal delays in healthcare access, financial and time costs burden on households, and the need to increase health literacy. These data also illustrate the impact of limited laboratory diagnostic equipment and tools on healthcare providers’ abilities to distinguish typhoid fever from other febrile conditions and treatment challenges associated with antimicrobial resistance. In light of these findings, there is an urgent need to identify and implement effective preventive measures including vaccination policies and programs focused on at-risk populations and endemic regions such as Nepal. Oxford University Press 2018-12-01 2017-07-29 /pmc/articles/PMC6226633/ /pubmed/28973415 http://dx.doi.org/10.1093/infdis/jix122 Text en © The Author(s) 2017. Published by Oxford University Press for the Infectious Diseases Society of America. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Supplement Articles
Kaljee, Linda M
Pach, Alfred
Garrett, Denise
Bajracharya, Deepak
Karki, Kshitji
Khan, Imran
Social and Economic Burden Associated With Typhoid Fever in Kathmandu and Surrounding Areas: A Qualitative Study
title Social and Economic Burden Associated With Typhoid Fever in Kathmandu and Surrounding Areas: A Qualitative Study
title_full Social and Economic Burden Associated With Typhoid Fever in Kathmandu and Surrounding Areas: A Qualitative Study
title_fullStr Social and Economic Burden Associated With Typhoid Fever in Kathmandu and Surrounding Areas: A Qualitative Study
title_full_unstemmed Social and Economic Burden Associated With Typhoid Fever in Kathmandu and Surrounding Areas: A Qualitative Study
title_short Social and Economic Burden Associated With Typhoid Fever in Kathmandu and Surrounding Areas: A Qualitative Study
title_sort social and economic burden associated with typhoid fever in kathmandu and surrounding areas: a qualitative study
topic Supplement Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226633/
https://www.ncbi.nlm.nih.gov/pubmed/28973415
http://dx.doi.org/10.1093/infdis/jix122
work_keys_str_mv AT kaljeelindam socialandeconomicburdenassociatedwithtyphoidfeverinkathmanduandsurroundingareasaqualitativestudy
AT pachalfred socialandeconomicburdenassociatedwithtyphoidfeverinkathmanduandsurroundingareasaqualitativestudy
AT garrettdenise socialandeconomicburdenassociatedwithtyphoidfeverinkathmanduandsurroundingareasaqualitativestudy
AT bajracharyadeepak socialandeconomicburdenassociatedwithtyphoidfeverinkathmanduandsurroundingareasaqualitativestudy
AT karkikshitji socialandeconomicburdenassociatedwithtyphoidfeverinkathmanduandsurroundingareasaqualitativestudy
AT khanimran socialandeconomicburdenassociatedwithtyphoidfeverinkathmanduandsurroundingareasaqualitativestudy