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Tau-induced focal neurotoxicity and network disruption related to apathy in Alzheimer’s disease

OBJECTIVE: Apathy is a common neuropsychological symptom in Alzheimer’s disease (AD), and previous studies demonstrated that neuronal loss and network disruption in some brain regions play pivotal roles in the pathogenesis of apathy. However, contributions of tau and amyloid-β (Aβ) depositions, path...

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Detalles Bibliográficos
Autores principales:	Kitamura, Soichiro, Shimada, Hitoshi, Niwa, Fumitoshi, Endo, Hironobu, Shinotoh, Hitoshi, Takahata, Keisuke, Kubota, Manabu, Takado, Yuhei, Hirano, Shigeki, Kimura, Yasuyuki, Zhang, Ming-Rong, Kuwabara, Satoshi, Suhara, Tetsuya, Higuchi, Makoto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2018
Materias:	Neuropsychiatry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6227800/ https://www.ncbi.nlm.nih.gov/pubmed/29884723 http://dx.doi.org/10.1136/jnnp-2018-317970

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