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Small molecules modified biomimetic gelatin/hydroxyapatite nanofibers constructing an ideal osteogenic microenvironment with significantly enhanced cranial bone formation

BACKGROUND: Repair of nonunion critical-sized bone defects is a significant clinical challenge all over the world. Construction of osteogenic microenvironment that provides osteoconductive and osteoinductive signals is a leading strategy. MATERIALS AND METHODS: In the present study, ascorbic acid (A...

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Detalles Bibliográficos
Autores principales: Li, Daowei, Zhang, Kai, Shi, Ce, Liu, Lijun, Yan, Guangxing, Liu, Cangwei, Zhou, Yijun, Hu, Yue, Sun, Hongchen, Yang, Bai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6228053/
https://www.ncbi.nlm.nih.gov/pubmed/30464466
http://dx.doi.org/10.2147/IJN.S174553

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