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PromoterPredict: sequence-based modelling of Escherichia coli σ(70) promoter strength yields logarithmic dependence between promoter strength and sequence

We present PromoterPredict, a dynamic multiple regression approach to predict the strength of Escherichia coli promoters binding the σ(70) factor of RNA polymerase. σ(70) promoters are ubiquitously used in recombinant DNA technology, but characterizing their strength is demanding in terms of both ti...

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Detalles Bibliográficos
Autores principales: Bharanikumar, Ramit, Premkumar, Keshav Aditya R., Palaniappan, Ashok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6228582/
https://www.ncbi.nlm.nih.gov/pubmed/30425888
http://dx.doi.org/10.7717/peerj.5862