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Integrative analysis of single-cell expression data reveals distinct regulatory states in bidirectional promoters
BACKGROUND: Bidirectional promoters (BPs) are prevalent in eukaryotic genomes. However, it is poorly understood how the cell integrates different epigenomic information, such as transcription factor (TF) binding and chromatin marks, to drive gene expression at BPs. Single-cell sequencing technologie...
Autores principales: | Behjati Ardakani, Fatemeh, Kattler, Kathrin, Nordström, Karl, Gasparoni, Nina, Gasparoni, Gilles, Fuchs, Sarah, Sinha, Anupam, Barann, Matthias, Ebert, Peter, Fischer, Jonas, Hutter, Barbara, Zipprich, Gideon, Imbusch, Charles D., Felder, Bärbel, Eils, Jürgen, Brors, Benedikt, Lengauer, Thomas, Manke, Thomas, Rosenstiel, Philip, Walter, Jörn, Schulz, Marcel H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230222/ https://www.ncbi.nlm.nih.gov/pubmed/30414612 http://dx.doi.org/10.1186/s13072-018-0236-7 |
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