Two histologically colorectal carcinomas subsets from the serrated pathway show different methylome signatures and diagnostic biomarkers

BACKGROUND: Altered methylation patterns are driving forces in colorectal carcinogenesis. The serrated adenocarcinoma (SAC) and sporadic colorectal carcinoma showing histological and molecular features of microsatellite instability (hmMSI-H) are two endpoints of the so-called serrated pathological r...

Descripción completa

Detalles Bibliográficos
Autores principales: García-Solano, José, Turpin, María C., Torres-Moreno, Daniel, Huertas-López, Francisco, Tuomisto, Anne, Mäkinen, Markus J., Conesa, Ana, Conesa-Zamora, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230233/
https://www.ncbi.nlm.nih.gov/pubmed/30413173
http://dx.doi.org/10.1186/s13148-018-0571-3

Ejemplares similares

Ejemplares similares