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Partial reduction of microglia does not affect tau pathology in aged mice
BACKGROUND: Activation of inflammation pathways in the brain occurs in Alzheimer’s disease and may contribute to the accumulation and spread of pathological proteins including tau. The goal of this study was to identify how changes in microglia, a key inflammatory cell type, may contribute to tau pr...
Autores principales: | Bennett, Rachel E., Bryant, Annie, Hu, Miwei, Robbins, Ashley B., Hopp, Sarah C., Hyman, Bradley T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230271/ https://www.ncbi.nlm.nih.gov/pubmed/30413160 http://dx.doi.org/10.1186/s12974-018-1348-5 |
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