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Salvianolic Acid A Attenuates Endoplasmic Reticulum Stress and Protects Against Cholestasis-Induced Liver Fibrosis via the SIRT1/HSF1 Pathway
Background: Endoplasmic reticulum stress (ER stress) plays a critical role in the pathogenesis of liver fibrosis; thus, it can be a potential therapeutic target of fibrosis. However, the mechanism of ER stress regulation in fibrosis, particularly through sirtuin 1 (SIRT1), remains unclear. The objec...
Autores principales: | Zhu, Jie, Wang, Ruiwen, Xu, Ting, Zhang, Shuai, Zhao, Yan, Li, Zhenlu, Wang, Chao, Zhou, Junjun, Gao, Dongyan, Hu, Yan, Tian, Xiaofeng, Yao, Jihong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230567/ https://www.ncbi.nlm.nih.gov/pubmed/30455644 http://dx.doi.org/10.3389/fphar.2018.01277 |
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