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N-Substituted Pyrido-1,4-Oxazin-3-Ones Induce Apoptosis of Hepatocellular Carcinoma Cells by Targeting NF-κB Signaling Pathway

Hepatocellular carcinoma (HCC) is a fatal disease and ranked fifth in cancer related mortality. Persistent activation of NF-κB is responsible for the oncogenesis, metastasis, tumor evasion, anti-apoptosis, angiogenesis and proliferation in HCC. Therefore, designing of chemically novel, biologically...

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Detalles Bibliográficos
Autores principales:	Mohan, Chakrabhavi Dhananjaya, Bharathkumar, Hanumantharayappa, Dukanya, Rangappa, Shobith, Shanmugam, Muthu K., Chinnathambi, Arunachalam, Alharbi, Sulaiman Ali, Alahmadi, Tahani Awad, Bhattacharjee, Atanu, Lobie, Peter E., Deivasigamani, Amudha, Hui, Kam Man, Sethi, Gautam, Basappa, Rangappa, Kanchugarakoppal S., Kumar, Alan Prem
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230568/ https://www.ncbi.nlm.nih.gov/pubmed/30455641 http://dx.doi.org/10.3389/fphar.2018.01125

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