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The Vacuolar Pathway in Macrophages Plays a Major Role in Antigen Cross-Presentation Induced by the Pore-Forming Protein Sticholysin II Encapsulated Into Liposomes
Cross-presentation is an important mechanism for the differentiation of effector cytotoxic T lymphocytes (CTL) from naïve CD8(+) T-cells, a key response for the clearance of intracellular pathogens and tumors. The liposomal co-encapsulation of the pore-forming protein sticholysin II (StII) with oval...
Autores principales: | Cruz-Leal, Yoelys, Grubaugh, Daniel, Nogueira, Catarina V., Lopetegui-González, Isbel, del Valle, Anaixis, Escalona, Felipe, Laborde, Rady J., Alvarez, Carlos, Fernández, Luis E., Starnbach, Michael N., Higgins, Darren E., Lanio, María E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230584/ https://www.ncbi.nlm.nih.gov/pubmed/30455685 http://dx.doi.org/10.3389/fimmu.2018.02473 |
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