Severe cholestatic jaundice associated with Graves’ disease

We describe a rare case of Graves’ disease presenting with atrial fibrillation and severe cholestasis. An extensive evaluation for hepatobiliary causes of cholestasis, including hepatic biopsy, was entirely negative. He was successfully treated with methimazole and eventual thyroidectomy. With cauti...

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Detalles Bibliográficos
Autores principales: Abebe, Abebe, Eck, Leigh M., Holyoak, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230595/
https://www.ncbi.nlm.nih.gov/pubmed/30455929
http://dx.doi.org/10.1002/ccr3.1859
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author Abebe, Abebe
Eck, Leigh M.
Holyoak, Michael
author_facet Abebe, Abebe
Eck, Leigh M.
Holyoak, Michael
author_sort Abebe, Abebe
collection PubMed
description We describe a rare case of Graves’ disease presenting with atrial fibrillation and severe cholestasis. An extensive evaluation for hepatobiliary causes of cholestasis, including hepatic biopsy, was entirely negative. He was successfully treated with methimazole and eventual thyroidectomy. With caution, thionamides can be utilized successfully for such patients.
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spelling pubmed-62305952018-11-19 Severe cholestatic jaundice associated with Graves’ disease Abebe, Abebe Eck, Leigh M. Holyoak, Michael Clin Case Rep Case Reports We describe a rare case of Graves’ disease presenting with atrial fibrillation and severe cholestasis. An extensive evaluation for hepatobiliary causes of cholestasis, including hepatic biopsy, was entirely negative. He was successfully treated with methimazole and eventual thyroidectomy. With caution, thionamides can be utilized successfully for such patients. John Wiley and Sons Inc. 2018-10-12 /pmc/articles/PMC6230595/ /pubmed/30455929 http://dx.doi.org/10.1002/ccr3.1859 Text en © 2018 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Case Reports
Abebe, Abebe
Eck, Leigh M.
Holyoak, Michael
Severe cholestatic jaundice associated with Graves’ disease
title Severe cholestatic jaundice associated with Graves’ disease
title_full Severe cholestatic jaundice associated with Graves’ disease
title_fullStr Severe cholestatic jaundice associated with Graves’ disease
title_full_unstemmed Severe cholestatic jaundice associated with Graves’ disease
title_short Severe cholestatic jaundice associated with Graves’ disease
title_sort severe cholestatic jaundice associated with graves’ disease
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230595/
https://www.ncbi.nlm.nih.gov/pubmed/30455929
http://dx.doi.org/10.1002/ccr3.1859
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