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Nivolumab‐induced severe acute kidney injury with a long latent phase in a patient with non‐small‐cell lung cancer: A case report

In the treatment of immunotherapy with immune checkpoint inhibitors, we often experience immune‐related adverse event which manifest most frequently as a skin disorder, and very rarely as a renal disorder. In our manuscript, we report the case of a 71‐year‐old man with nivolumab‐induced severe acute...

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Detalles Bibliográficos
Autores principales: Uchida, Naohiro, Tsuji, Seijiro, Fujita, Kohei, Koizumi, Mitsuteru, Moriyoshi, Koki, Mio, Tadashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230597/
https://www.ncbi.nlm.nih.gov/pubmed/30455917
http://dx.doi.org/10.1002/ccr3.1848
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author Uchida, Naohiro
Tsuji, Seijiro
Fujita, Kohei
Koizumi, Mitsuteru
Moriyoshi, Koki
Mio, Tadashi
author_facet Uchida, Naohiro
Tsuji, Seijiro
Fujita, Kohei
Koizumi, Mitsuteru
Moriyoshi, Koki
Mio, Tadashi
author_sort Uchida, Naohiro
collection PubMed
description In the treatment of immunotherapy with immune checkpoint inhibitors, we often experience immune‐related adverse event which manifest most frequently as a skin disorder, and very rarely as a renal disorder. In our manuscript, we report the case of a 71‐year‐old man with nivolumab‐induced severe acute kidney injury (AKI) in which the time from treatment initiation to the onset of AKI was the longest among the previously reported cases (377 days). Prolonged follow‐up is therefore warranted to detect late‐onset AKI.
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spelling pubmed-62305972018-11-19 Nivolumab‐induced severe acute kidney injury with a long latent phase in a patient with non‐small‐cell lung cancer: A case report Uchida, Naohiro Tsuji, Seijiro Fujita, Kohei Koizumi, Mitsuteru Moriyoshi, Koki Mio, Tadashi Clin Case Rep Case Reports In the treatment of immunotherapy with immune checkpoint inhibitors, we often experience immune‐related adverse event which manifest most frequently as a skin disorder, and very rarely as a renal disorder. In our manuscript, we report the case of a 71‐year‐old man with nivolumab‐induced severe acute kidney injury (AKI) in which the time from treatment initiation to the onset of AKI was the longest among the previously reported cases (377 days). Prolonged follow‐up is therefore warranted to detect late‐onset AKI. John Wiley and Sons Inc. 2018-10-02 /pmc/articles/PMC6230597/ /pubmed/30455917 http://dx.doi.org/10.1002/ccr3.1848 Text en © 2018 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Case Reports
Uchida, Naohiro
Tsuji, Seijiro
Fujita, Kohei
Koizumi, Mitsuteru
Moriyoshi, Koki
Mio, Tadashi
Nivolumab‐induced severe acute kidney injury with a long latent phase in a patient with non‐small‐cell lung cancer: A case report
title Nivolumab‐induced severe acute kidney injury with a long latent phase in a patient with non‐small‐cell lung cancer: A case report
title_full Nivolumab‐induced severe acute kidney injury with a long latent phase in a patient with non‐small‐cell lung cancer: A case report
title_fullStr Nivolumab‐induced severe acute kidney injury with a long latent phase in a patient with non‐small‐cell lung cancer: A case report
title_full_unstemmed Nivolumab‐induced severe acute kidney injury with a long latent phase in a patient with non‐small‐cell lung cancer: A case report
title_short Nivolumab‐induced severe acute kidney injury with a long latent phase in a patient with non‐small‐cell lung cancer: A case report
title_sort nivolumab‐induced severe acute kidney injury with a long latent phase in a patient with non‐small‐cell lung cancer: a case report
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230597/
https://www.ncbi.nlm.nih.gov/pubmed/30455917
http://dx.doi.org/10.1002/ccr3.1848
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