Splenic mass in a case of CALR‐mutated essential thrombocythemia

We report here an intrasplenic large mass in an elderly case of essential thrombocythemia (ET)‐myelofibrosis. Laparoscopic splenectomy revealed extramedullary hematopoiesis (EMH) and a type 1 CALR gene mutation (CALR‐c.1092_1143del52) in the splenic mass. It remains to be determined if CALR‐mutated...

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Detalles Bibliográficos
Autores principales: Imashuku, Shinsaku, Kotani, Shinichi, Hinami, Junsuke, Nishimura, Keisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Clinical Images
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230599/
https://www.ncbi.nlm.nih.gov/pubmed/30455943
http://dx.doi.org/10.1002/ccr3.1857
Descripción
Sumario:We report here an intrasplenic large mass in an elderly case of essential thrombocythemia (ET)‐myelofibrosis. Laparoscopic splenectomy revealed extramedullary hematopoiesis (EMH) and a type 1 CALR gene mutation (CALR‐c.1092_1143del52) in the splenic mass. It remains to be determined if CALR‐mutated ET has an increased tendency to develop mass‐forming EMH.

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