Splenic mass in a case of CALR‐mutated essential thrombocythemia

We report here an intrasplenic large mass in an elderly case of essential thrombocythemia (ET)‐myelofibrosis. Laparoscopic splenectomy revealed extramedullary hematopoiesis (EMH) and a type 1 CALR gene mutation (CALR‐c.1092_1143del52) in the splenic mass. It remains to be determined if CALR‐mutated...

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Autores principales: Imashuku, Shinsaku, Kotani, Shinichi, Hinami, Junsuke, Nishimura, Keisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Clinical Images
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230599/
https://www.ncbi.nlm.nih.gov/pubmed/30455943
http://dx.doi.org/10.1002/ccr3.1857
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author Imashuku, Shinsaku
Kotani, Shinichi
Hinami, Junsuke
Nishimura, Keisuke
author_facet Imashuku, Shinsaku
Kotani, Shinichi
Hinami, Junsuke
Nishimura, Keisuke
author_sort Imashuku, Shinsaku
collection PubMed
description We report here an intrasplenic large mass in an elderly case of essential thrombocythemia (ET)‐myelofibrosis. Laparoscopic splenectomy revealed extramedullary hematopoiesis (EMH) and a type 1 CALR gene mutation (CALR‐c.1092_1143del52) in the splenic mass. It remains to be determined if CALR‐mutated ET has an increased tendency to develop mass‐forming EMH.
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spelling pubmed-62305992018-11-19 Splenic mass in a case of CALR‐mutated essential thrombocythemia Imashuku, Shinsaku Kotani, Shinichi Hinami, Junsuke Nishimura, Keisuke Clin Case Rep Clinical Images We report here an intrasplenic large mass in an elderly case of essential thrombocythemia (ET)‐myelofibrosis. Laparoscopic splenectomy revealed extramedullary hematopoiesis (EMH) and a type 1 CALR gene mutation (CALR‐c.1092_1143del52) in the splenic mass. It remains to be determined if CALR‐mutated ET has an increased tendency to develop mass‐forming EMH. John Wiley and Sons Inc. 2018-10-09 /pmc/articles/PMC6230599/ /pubmed/30455943 http://dx.doi.org/10.1002/ccr3.1857 Text en © 2018 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Clinical Images
Imashuku, Shinsaku
Kotani, Shinichi
Hinami, Junsuke
Nishimura, Keisuke
Splenic mass in a case of CALR‐mutated essential thrombocythemia
title Splenic mass in a case of CALR‐mutated essential thrombocythemia
title_full Splenic mass in a case of CALR‐mutated essential thrombocythemia
title_fullStr Splenic mass in a case of CALR‐mutated essential thrombocythemia
title_full_unstemmed Splenic mass in a case of CALR‐mutated essential thrombocythemia
title_short Splenic mass in a case of CALR‐mutated essential thrombocythemia
title_sort splenic mass in a case of calr‐mutated essential thrombocythemia
topic Clinical Images
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230599/
https://www.ncbi.nlm.nih.gov/pubmed/30455943
http://dx.doi.org/10.1002/ccr3.1857
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