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T cell Allorecognition Pathways in Solid Organ Transplantation
Transplantation is unusual in that T cells can recognize alloantigen by at least two distinct pathways: as intact MHC alloantigen on the surface of donor cells via the direct pathway; and as self-restricted processed alloantigen via the indirect pathway. Direct pathway responses are viewed as strong...
Autores principales: | Siu, Jacqueline H. Y., Surendrakumar, Veena, Richards, James A., Pettigrew, Gavin J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230624/ https://www.ncbi.nlm.nih.gov/pubmed/30455697 http://dx.doi.org/10.3389/fimmu.2018.02548 |
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