First detection and molecular characterization of a DENV‐1/DENV‐4 co‐infection during an epidemic in Rio de Janeiro, Brazil

In the 80s, dengue viruses type 1 and 4 (DENV‐1 and 4) were isolated in North region of Brazil. However, it was only after the DENV‐1 introduction in the state of Rio de Janeiro (RJ) in mid‐1980s, that dengue became a nationwide public health problem. In 2009, this serotype re‐emerged causing an exp...

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Detalles Bibliográficos
Autores principales: de Bruycker‐Nogueira, Fernanda, Faria, Nieli Rodrigues da Costa, Nunes, Priscila Conrado Guerra, Nogueira, Rita Maria Ribeiro, de Filippis, Ana Maria Bispo, dos Santos, Flavia Barreto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230646/
https://www.ncbi.nlm.nih.gov/pubmed/30455894
http://dx.doi.org/10.1002/ccr3.1750
Descripción
Sumario:In the 80s, dengue viruses type 1 and 4 (DENV‐1 and 4) were isolated in North region of Brazil. However, it was only after the DENV‐1 introduction in the state of Rio de Janeiro (RJ) in mid‐1980s, that dengue became a nationwide public health problem. In 2009, this serotype re‐emerged causing an explosive epidemic in the country. DENV‐4 was first detected in RJ in 2011 and in 2012, and DENV‐1 and 4 were co‐circulating and responsible for a high number of cases notifications. Here, we describe the detection and molecular characterization of a DENV‐1/4 co‐infection in sample of 2012 in RJ.

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