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Human Dendritic Cell Subsets Undergo Distinct Metabolic Reprogramming for Immune Response

Toll-like receptor (TLR) agonists induce metabolic reprogramming, which is required for immune activation. We have investigated mechanisms that regulate metabolic adaptation upon TLR-stimulation in human blood DC subsets, CD1c(+) myeloid DCs (mDCs) and plasmacytoid DCs (pDCs). We show that TLR-stimu...

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Detalles Bibliográficos
Autores principales:	Basit, Farhan, Mathan, Till, Sancho, David, de Vries, I. Jolanda M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230993/ https://www.ncbi.nlm.nih.gov/pubmed/30455688 http://dx.doi.org/10.3389/fimmu.2018.02489

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