Paraneoplastic PRES from lymphoma induced hypercalcemia: Case report and review of the literature

Hypercalcemia from tumors has been associated with Posterior Reversible Encephalopathy Syndrome (PRES) but the mechanism remains unclear. In this article, we describe a case of PRES caused by hypercalcemia from lymphoma. We summarize the available scientific evidence linking hypercalcemia to failure...

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Detalles Bibliográficos
Autores principales: Moussawi, Khaled, Meltzer, Ethan I., Levin, Seth N., Prasad, Sashank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231055/
https://www.ncbi.nlm.nih.gov/pubmed/30456318
http://dx.doi.org/10.1016/j.ensci.2018.11.003
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author Moussawi, Khaled
Meltzer, Ethan I.
Levin, Seth N.
Prasad, Sashank
author_facet Moussawi, Khaled
Meltzer, Ethan I.
Levin, Seth N.
Prasad, Sashank
author_sort Moussawi, Khaled
collection PubMed
description Hypercalcemia from tumors has been associated with Posterior Reversible Encephalopathy Syndrome (PRES) but the mechanism remains unclear. In this article, we describe a case of PRES caused by hypercalcemia from lymphoma. We summarize the available scientific evidence linking hypercalcemia to failure of cerebral autoregulation and potentially PRES. A major link is the hypomagnesemia induced by hypercalcemia. While this concept requires further clinical testing and validation, it is clinically significant for the management of PRES, even when not directly caused by hypercalcemia.
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spelling pubmed-62310552018-11-19 Paraneoplastic PRES from lymphoma induced hypercalcemia: Case report and review of the literature Moussawi, Khaled Meltzer, Ethan I. Levin, Seth N. Prasad, Sashank eNeurologicalSci Case Report Hypercalcemia from tumors has been associated with Posterior Reversible Encephalopathy Syndrome (PRES) but the mechanism remains unclear. In this article, we describe a case of PRES caused by hypercalcemia from lymphoma. We summarize the available scientific evidence linking hypercalcemia to failure of cerebral autoregulation and potentially PRES. A major link is the hypomagnesemia induced by hypercalcemia. While this concept requires further clinical testing and validation, it is clinically significant for the management of PRES, even when not directly caused by hypercalcemia. Elsevier 2018-11-02 /pmc/articles/PMC6231055/ /pubmed/30456318 http://dx.doi.org/10.1016/j.ensci.2018.11.003 Text en http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Moussawi, Khaled
Meltzer, Ethan I.
Levin, Seth N.
Prasad, Sashank
Paraneoplastic PRES from lymphoma induced hypercalcemia: Case report and review of the literature
title Paraneoplastic PRES from lymphoma induced hypercalcemia: Case report and review of the literature
title_full Paraneoplastic PRES from lymphoma induced hypercalcemia: Case report and review of the literature
title_fullStr Paraneoplastic PRES from lymphoma induced hypercalcemia: Case report and review of the literature
title_full_unstemmed Paraneoplastic PRES from lymphoma induced hypercalcemia: Case report and review of the literature
title_short Paraneoplastic PRES from lymphoma induced hypercalcemia: Case report and review of the literature
title_sort paraneoplastic pres from lymphoma induced hypercalcemia: case report and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231055/
https://www.ncbi.nlm.nih.gov/pubmed/30456318
http://dx.doi.org/10.1016/j.ensci.2018.11.003
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