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Prior Knowledge Driven Joint NMF Algorithm for ceRNA Co-Module Identification

MRNA and lncRNA serve as a type of endogenous RNA in cell, which can competitively bind to the same miRNA through miRNA response elements (MREs), thereby regulating their respective expression levels, playing an important role in post-transcriptional regulation, and regulating the progress of tumors...

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Detalles Bibliográficos
Autores principales: Deng, Jin, Kong, Wei, Wang, Shuaiqun, Mou, Xiaoyang, Zeng, Weiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231218/
https://www.ncbi.nlm.nih.gov/pubmed/30443186
http://dx.doi.org/10.7150/ijbs.27555