Healthy elderly Singaporeans show no age-related humoral hyporesponsiveness nor diminished plasmablast generation in response to influenza vaccine

ABSTRACT: Improving influenza vaccine efficacy is a priority to reduce the burden of influenza-associated morbidity and mortality. By careful selection of individuals based on health we show sustained response to influenza vaccination in older adults. Sustaining health in aging could be an important...

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Detalles Bibliográficos
Autores principales: Camous, Xavier, Visan, Lucian, Ying, Crystal Tan Tze, Abel, Brian, Nyunt, Ma Shwe Zin, Narang, Vipin, Poidinger, Michael, Carre, Christophe, Sesay, Sanie, Bosco, Nabil, Burdin, Nicolas, Tambyah, Paul Anantharajah, Pin, Ng Tze, Larbi, Anis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231250/
https://www.ncbi.nlm.nih.gov/pubmed/30455722
http://dx.doi.org/10.1186/s12979-018-0137-4
Descripción
Sumario:ABSTRACT: Improving influenza vaccine efficacy is a priority to reduce the burden of influenza-associated morbidity and mortality. By careful selection of individuals based on health we show sustained response to influenza vaccination in older adults. Sustaining health in aging could be an important player in maintaining immune responses to influenza vaccination. TRIAL REGISTRATION: NCT03266237. Registered 30 August 2017, https://clinicaltrials.gov/ct2/show/NCT03266237.

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