Healthy elderly Singaporeans show no age-related humoral hyporesponsiveness nor diminished plasmablast generation in response to influenza vaccine

ABSTRACT: Improving influenza vaccine efficacy is a priority to reduce the burden of influenza-associated morbidity and mortality. By careful selection of individuals based on health we show sustained response to influenza vaccination in older adults. Sustaining health in aging could be an important...

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Autores principales: Camous, Xavier, Visan, Lucian, Ying, Crystal Tan Tze, Abel, Brian, Nyunt, Ma Shwe Zin, Narang, Vipin, Poidinger, Michael, Carre, Christophe, Sesay, Sanie, Bosco, Nabil, Burdin, Nicolas, Tambyah, Paul Anantharajah, Pin, Ng Tze, Larbi, Anis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231250/
https://www.ncbi.nlm.nih.gov/pubmed/30455722
http://dx.doi.org/10.1186/s12979-018-0137-4
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author Camous, Xavier
Visan, Lucian
Ying, Crystal Tan Tze
Abel, Brian
Nyunt, Ma Shwe Zin
Narang, Vipin
Poidinger, Michael
Carre, Christophe
Sesay, Sanie
Bosco, Nabil
Burdin, Nicolas
Tambyah, Paul Anantharajah
Pin, Ng Tze
Larbi, Anis
author_facet Camous, Xavier
Visan, Lucian
Ying, Crystal Tan Tze
Abel, Brian
Nyunt, Ma Shwe Zin
Narang, Vipin
Poidinger, Michael
Carre, Christophe
Sesay, Sanie
Bosco, Nabil
Burdin, Nicolas
Tambyah, Paul Anantharajah
Pin, Ng Tze
Larbi, Anis
author_sort Camous, Xavier
collection PubMed
description ABSTRACT: Improving influenza vaccine efficacy is a priority to reduce the burden of influenza-associated morbidity and mortality. By careful selection of individuals based on health we show sustained response to influenza vaccination in older adults. Sustaining health in aging could be an important player in maintaining immune responses to influenza vaccination. TRIAL REGISTRATION: NCT03266237. Registered 30 August 2017, https://clinicaltrials.gov/ct2/show/NCT03266237.
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spelling pubmed-62312502018-11-19 Healthy elderly Singaporeans show no age-related humoral hyporesponsiveness nor diminished plasmablast generation in response to influenza vaccine Camous, Xavier Visan, Lucian Ying, Crystal Tan Tze Abel, Brian Nyunt, Ma Shwe Zin Narang, Vipin Poidinger, Michael Carre, Christophe Sesay, Sanie Bosco, Nabil Burdin, Nicolas Tambyah, Paul Anantharajah Pin, Ng Tze Larbi, Anis Immun Ageing Letter to the Editor ABSTRACT: Improving influenza vaccine efficacy is a priority to reduce the burden of influenza-associated morbidity and mortality. By careful selection of individuals based on health we show sustained response to influenza vaccination in older adults. Sustaining health in aging could be an important player in maintaining immune responses to influenza vaccination. TRIAL REGISTRATION: NCT03266237. Registered 30 August 2017, https://clinicaltrials.gov/ct2/show/NCT03266237. BioMed Central 2018-11-12 /pmc/articles/PMC6231250/ /pubmed/30455722 http://dx.doi.org/10.1186/s12979-018-0137-4 Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Letter to the Editor
Camous, Xavier
Visan, Lucian
Ying, Crystal Tan Tze
Abel, Brian
Nyunt, Ma Shwe Zin
Narang, Vipin
Poidinger, Michael
Carre, Christophe
Sesay, Sanie
Bosco, Nabil
Burdin, Nicolas
Tambyah, Paul Anantharajah
Pin, Ng Tze
Larbi, Anis
Healthy elderly Singaporeans show no age-related humoral hyporesponsiveness nor diminished plasmablast generation in response to influenza vaccine
title Healthy elderly Singaporeans show no age-related humoral hyporesponsiveness nor diminished plasmablast generation in response to influenza vaccine
title_full Healthy elderly Singaporeans show no age-related humoral hyporesponsiveness nor diminished plasmablast generation in response to influenza vaccine
title_fullStr Healthy elderly Singaporeans show no age-related humoral hyporesponsiveness nor diminished plasmablast generation in response to influenza vaccine
title_full_unstemmed Healthy elderly Singaporeans show no age-related humoral hyporesponsiveness nor diminished plasmablast generation in response to influenza vaccine
title_short Healthy elderly Singaporeans show no age-related humoral hyporesponsiveness nor diminished plasmablast generation in response to influenza vaccine
title_sort healthy elderly singaporeans show no age-related humoral hyporesponsiveness nor diminished plasmablast generation in response to influenza vaccine
topic Letter to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231250/
https://www.ncbi.nlm.nih.gov/pubmed/30455722
http://dx.doi.org/10.1186/s12979-018-0137-4
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