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Oligo swapping method for in vitro DNA repair substrate containing a single DNA lesion at a specific site
BACKGROUND: A wide variety of DNA lesions interfere with replication and transcription, leading to mutations and cell death. DNA repair mechanisms act upon these DNA lesions present in the genomic DNA. To investigate a DNA repair mechanism elaborately, an in vitro DNA repair substrate containing DNA...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231255/ https://www.ncbi.nlm.nih.gov/pubmed/30459925 http://dx.doi.org/10.1186/s41021-018-0112-5 |