Cargando…

SETD2 mutations in primary central nervous system tumors

Mutations in SETD2 are found in many tumors, including central nervous system (CNS) tumors. Previous work has shown these mutations occur specifically in high grade gliomas of the cerebral hemispheres in pediatric and young adult patients. We investigated SETD2 mutations in a cohort of approximately...

Descripción completa

Detalles Bibliográficos
Autores principales:	Viaene, Angela N., Santi, Mariarita, Rosenbaum, Jason, Li, Marilyn M., Surrey, Lea F., Nasrallah, MacLean P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231273/ https://www.ncbi.nlm.nih.gov/pubmed/30419952 http://dx.doi.org/10.1186/s40478-018-0623-0

Ejemplares similares

Congenital tumors of the central nervous system: an institutional review of 64 cases with emphasis on tumors with unique histologic and molecular characteristics
por: Viaene, Angela N., et al.
Publicado: (2020)

The spectrum of rare central nervous system (CNS) tumors with EWSR1‐non‐ETS fusions: experience from three pediatric institutions with review of the literature
por: Lopez‐Nunez, Oscar, et al.
Publicado: (2020)

Histologic, immunohistochemical, and molecular features of pituicytomas and atypical pituicytomas
por: Viaene, Angela N., et al.
Publicado: (2019)

EPEN-06. CELL ECOSYSTEM AND SIGNALING PATHWAYS OF PRIMARY AND METASTATIC PEDIATRIC POSTERIOR FOSSA EPENDYMOMA
por: Aubin, Rachael, et al.
Publicado: (2021)

Histone H3K27 Dimethyl Loss is Highly Specific for Malignant Peripheral Nerve Sheath Tumor and Distinguishes True PRC2 Loss from Isolated H3K27 Trimethyl Loss
por: Marchione, Dylan M, et al.
Publicado: (2019)

A dual-genotype oligoastrocytoma with histologic, molecular, radiological and time-course features
por: Nasrallah, Mac Lean P., et al.
Publicado: (2020)

Novel FGFR2-INA fusion identified in two low-grade mixed neuronal-glial tumors drives oncogenesis via MAPK and PI3K/mTOR pathway activation
por: Jain, Payal, et al.
Publicado: (2018)

An Unusual Coexistence of Primary Central Nervous System Non-Hodgkin's Lymphoma and Acute Promyelocytic Leukemia
por: Fracchiolla, Nicola Stefano, et al.
Publicado: (2018)

Mutational analysis of primary central nervous system lymphoma
por: Bruno, Aurélie, et al.
Publicado: (2014)

Rare Primary Central Nervous System Tumors
por: Kubicky, Charlotte Dai, et al.
Publicado: (2014)

B7–H3 as a Prognostic Biomarker and Therapeutic Target in Pediatric central nervous system Tumors
por: Maachani, Uday B., et al.
Publicado: (2019)

MODL-28. Patient-derived, three-dimensional organoid platform for pediatric brain tumor modeling
por: Baubet, Valerie, et al.
Publicado: (2022)

SETD2 variation correlates with tumor mutational burden and MSI along with improved response to immunotherapy
por: Zheng, Xiaobin, et al.
Publicado: (2023)

SETD2: an epigenetic modifier with tumor suppressor functionality
por: Li, Jun, et al.
Publicado: (2016)

Recurrent SETD2 mutation in NPM1-mutated acute myeloid leukemia
por: Sun, Jiewen, et al.
Publicado: (2020)

SETD3 is an Actin Histidine Methyltransferase that Prevents Primary Dystocia
por: Wilkinson, Alex W., et al.
Publicado: (2019)

Epigenotype–genotype–phenotype correlations in SETD1A and SETD2 chromatin disorders
por: Lee, Sunwoo, et al.
Publicado: (2023)

Novel ATXN1/ATXN1L::NUTM2A fusions identified in aggressive infant sarcomas with gene expression and methylation patterns similar to CIC-rearranged sarcoma
por: Xu, Feng, et al.
Publicado: (2022)

Pro-inflammatory cytokines mediate the epithelial-to-mesenchymal-like transition of pediatric posterior fossa ependymoma
por: Aubin, Rachael G., et al.
Publicado: (2022)

Modulation of Tumor Tolerance in Primary Central Nervous System Malignancies
por: Johnson, Theodore S., et al.
Publicado: (2012)

Prolactin gene expression in primary central nervous system tumors
por: Mendes, Graziella Alebrant, et al.
Publicado: (2013)

Rare Primary Central Nervous System Tumors in Adults: An Overview
por: Franceschi, Enrico, et al.
Publicado: (2020)

THU237 A Case Of Primary Hypothyroidism, Dysglycemia And Epilepsy With PAX8 And SETD1A Mutation
por: Singh, Santosh Kumar
Publicado: (2023)

Neuropathology associated with SARS-CoV-2 infection
por: Nasrallah, MacLean P, et al.
Publicado: (2021)

Diffuse leptomeningeal glioneuronal tumor in a child masquerading as an intramedullary spinal pilocytic astrocytoma
por: Madsen, Peter J, et al.
Publicado: (2023)

Mutations in epigenetic regulators including SETD2 are gained during relapse in pediatric acute lymphoblastic leukemia
por: Mar, Brenton G, et al.
Publicado: (2014)

Pan-cancer analysis of SETD2 mutation and its association with the efficacy of immunotherapy
por: Lu, Mingdong, et al.
Publicado: (2021)

Clinical utility of custom-designed NGS panel testing in pediatric tumors
por: Surrey, Lea F., et al.
Publicado: (2019)

Incidence of Primary Central Nervous System Tumors Among the Hispanic Population in Texas 1995-2013
por: Ambe, Solomon, et al.
Publicado: (2020)

DUBing Primary Tumors of the Central Nervous System: Regulatory Roles of Deubiquitinases
por: Klonisch, Thomas, et al.
Publicado: (2023)

Immunotherapy associated central nervous system complications in primary brain tumors
por: Mantica, Megan, et al.
Publicado: (2023)

Clinical Evaluation of IDH Mutation Status in Formalin-Fixed Paraffin-Embedded Tissue in Gliomas
por: Nelson, Ernest J., et al.
Publicado: (2023)

METB-08. GENOMIC AND MOLECULAR PROFILING OF PEDIATRIC CENTRAL NERVOUS SYSTEM TUMORS: A SINGLE INSTITUTION ANALYSIS
por: Kline, Cassie, et al.
Publicado: (2023)

Sequence specificity analysis of the SETD2 protein lysine methyltransferase and discovery of a SETD2 super-substrate
por: Schuhmacher, Maren Kirstin, et al.
Publicado: (2020)

Primary Central Nervous System Lymphoma
por: Dong, Yan-Hong, et al.
Publicado: (2016)

Primary central nervous system lymphoma
por: Gloghini, Annunziata, et al.
Publicado: (2015)

Primary Central Nervous System Fibrosarcoma
por: Vinodh, VP, et al.
Publicado: (2017)

Primary central nervous system lymphoma
por: Löw, Sarah, et al.
Publicado: (2018)

Neurobehavioral characteristics of mice with SETD5 mutations as models of IDD23 and KBG syndromes
por: Nakagawa, Tadashi, et al.
Publicado: (2023)

Pediatric brain tumors: A neuropathologist's approach to the integrated diagnosis
por: Viaene, Angela N.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_0tbalmu03693sb048h0oiqu0s4