Resveratrol Decreases Oxidative Stress by Restoring Mitophagy and Improves the Pathophysiology of Dystrophin-Deficient mdx Mice

We previously showed that treatment with resveratrol (3,5,4′-trihydroxy-trans-stilbene), an activator of the NAD(+)-dependent deacetylase SIRT1 at 4 g/kg food for 32 weeks, significantly decreased the muscular reactive oxygen species (ROS) levels and ameliorated the pathology of mdx mice, an animal...

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Detalles Bibliográficos
Autores principales: Sebori, Rio, Kuno, Atsushi, Hosoda, Ryusuke, Hayashi, Takashi, Horio, Yoshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231358/
https://www.ncbi.nlm.nih.gov/pubmed/30510631
http://dx.doi.org/10.1155/2018/9179270

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231358/
https://www.ncbi.nlm.nih.gov/pubmed/30510631
http://dx.doi.org/10.1155/2018/9179270

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