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Identifying the Favored Mutation in a Positive Selective Sweep
Methods to identify signatures of selective sweeps in population genomics data have been actively developed, but mostly do not identify the specific mutation favored by selection. We present a method, iSAFE, that uses a statistic derived solely from population genetics signals to accurately pinpoint...
Autores principales: | Akbari, Ali, Vitti, Joseph J., Iranmehr, Arya, Bakhtiari, Mehrdad, Sabeti, Pardis C., Mirarab, Siavash, Bafna, Vineet |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231406/ https://www.ncbi.nlm.nih.gov/pubmed/29457793 http://dx.doi.org/10.1038/nmeth.4606 |
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