Notch inhibitor can attenuate apparent diffusion coefficient and improve neurological function through downregulating NOX2-ROS in severe traumatic brain injury

INTRODUCTION: Secondary brain injury is a major factor that affects the prognosis and outcome of traumatic brain injury (TBI) patients. Secondary brain edema is considered to be an initiating factor in secondary brain injury after TBI. A previous study has indicated that Notch signaling activation c...

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Detalles Bibliográficos
Autores principales: Zhang, Hong-Mei, Chen, Wei, Liu, Rui-Ning, Zhao, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231429/
https://www.ncbi.nlm.nih.gov/pubmed/30510400
http://dx.doi.org/10.2147/DDDT.S174037

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