Transcriptional co-expression regulatory network analysis for Snail and Slug identifies IL1R1, an inflammatory cytokine receptor, to be preferentially expressed in ST-EPN-RELA and PF-EPN-A molecular subgroups of intracranial ependymomas

Recent molecular subgrouping of ependymomas (EPN) by DNA methylation profiling has identified ST-EPN-RELA and PF-EPN-A subgroups to be associated with poor outcome. Snail/Slug are cardinal epithelial-to-mesenchymal transcription factors (EMT-TFs) and are overexpressed in several CNS tumors, includin...

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Detalles Bibliográficos
Autores principales: Malgulwar, Prit Benny, Sharma, Vikas, Tomar, Ashutosh Singh, Verma, Chaitenya, Nambirajan, Aruna, Singh, Manmohan, Suri, Vaishali, Sarkar, Chitra, Sharma, Mehar Chand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231457/
https://www.ncbi.nlm.nih.gov/pubmed/30464804
http://dx.doi.org/10.18632/oncotarget.26211

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