Association of coronary dominance with the severity of coronary artery disease: a cross-sectional study in Shaanxi Province, China

OBJECTIVE: To investigate whether coronary artery dominance is associated with the severity of coronary artery disease (CAD). DESIGN: Cross-sectional study. SETTING: Single-centre. PARTICIPANTS: Between July 2015 and February 2017, 1654 patients who underwent coronary angiography (CAG) were recruited into this cross-sectional study. MEASUREMENT AND METHODS: According to coronary dominance, patients were classified into left dominance (LD), right dominance (RD) and codominance (CD) based on the CAG results. Multiple linear regression analysis was performed to test the association between severity of CAD and coronary dominance. RESULTS: The total Gensini score was significantly higher in the RD group than in the left-CD group (42.3±33.6 vs 36.3±29.8; p=0.033). After adjusting for potential confounding factors, the results of multivariate linear regression showed that RD was associated with the severity of CAD (β=6.699, 95% CI 1.193 to 12.205, p=0.017). CONCLUSIONS: The results suggest that right coronary dominance was associated with the severity of CAD.