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Differential regulation of actin-activated nucleotidyl cyclase virulence factors by filamentous and globular actin

Several bacterial pathogens produce nucleotidyl cyclase toxins to manipulate eukaryotic host cells. Inside host cells they are activated by endogenous cofactors to produce high levels of cyclic nucleotides (cNMPs). The ExoY toxin from Pseudomonas aeruginosa (PaExoY) and the ExoY-like module (VnExoY)...

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Detalles Bibliográficos
Autores principales:	Raoux-Barbot, Dorothée, Belyy, Alexander, Worpenberg, Lina, Montluc, Sabrina, Deville, Celia, Henriot, Véronique, Velours, Christophe, Ladant, Daniel, Renault, Louis, Mechold, Undine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231621/ https://www.ncbi.nlm.nih.gov/pubmed/30419035 http://dx.doi.org/10.1371/journal.pone.0206133

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