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The Foxp3(+) regulatory T-cell population requires IL-4Rα signaling to control inflammation during helminth infections

Forkhead box P3 (Foxp3(+)) regulatory T (Treg)-cell function is controlled by environmental cues of which cytokine-mediated signaling is a dominant component. In vivo, interleukin-4 (IL-4)-mediated signaling via IL-4 receptor alpha (IL-4Rα) mediates Treg cell transdifferentiation into ex-Foxp3 T hel...

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Detalles Bibliográficos
Autores principales:	Abdel Aziz, Nada, Nono, Justin Komguep, Mpotje, Thabo, Brombacher, Frank
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231676/ https://www.ncbi.nlm.nih.gov/pubmed/30379806 http://dx.doi.org/10.1371/journal.pbio.2005850

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