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Recurrent Cholangiocarcinoma in Pregnancy: A Case Report
Hepatobiliary malignancies during pregnancy are extremely rare and portend a poor prognosis. There are only seven published cases of cholangiocarcinoma in an obstetrical patient, all are cases of primary cholangiocarcinoma (1–7). Herein, we describe the first case of recurrent cholangiocarcinoma dur...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Thieme Medical Publishers
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232044/ https://www.ncbi.nlm.nih.gov/pubmed/30425881 http://dx.doi.org/10.1055/s-0038-1675376 |
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author | Francis, Antonia P. Chang, Michelle Dolin, Cara D. Chervenak, Judith Cardonick, Elyce |
author_facet | Francis, Antonia P. Chang, Michelle Dolin, Cara D. Chervenak, Judith Cardonick, Elyce |
author_sort | Francis, Antonia P. |
collection | PubMed |
description | Hepatobiliary malignancies during pregnancy are extremely rare and portend a poor prognosis. There are only seven published cases of cholangiocarcinoma in an obstetrical patient, all are cases of primary cholangiocarcinoma (1–7). Herein, we describe the first case of recurrent cholangiocarcinoma during pregnancy. The patient did not receive chemotherapy during pregnancy and required prolonged hospitalizations for nutritional and intensive medical support. She delivered preterm, at 30 (2/7) weeks gestation, after developing pre-eclampsia with severe features. The infant was healthy, with no malformations, and currently exhibits no neurological or behavioral sequelae at 8months of age. We discuss themanagement considerations inherent to this complex clinical scenario including metastatic disease severity, ethical considerations, and palliative care treatment options. |
format | Online Article Text |
id | pubmed-6232044 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Thieme Medical Publishers |
record_format | MEDLINE/PubMed |
spelling | pubmed-62320442018-11-13 Recurrent Cholangiocarcinoma in Pregnancy: A Case Report Francis, Antonia P. Chang, Michelle Dolin, Cara D. Chervenak, Judith Cardonick, Elyce AJP Rep Hepatobiliary malignancies during pregnancy are extremely rare and portend a poor prognosis. There are only seven published cases of cholangiocarcinoma in an obstetrical patient, all are cases of primary cholangiocarcinoma (1–7). Herein, we describe the first case of recurrent cholangiocarcinoma during pregnancy. The patient did not receive chemotherapy during pregnancy and required prolonged hospitalizations for nutritional and intensive medical support. She delivered preterm, at 30 (2/7) weeks gestation, after developing pre-eclampsia with severe features. The infant was healthy, with no malformations, and currently exhibits no neurological or behavioral sequelae at 8months of age. We discuss themanagement considerations inherent to this complex clinical scenario including metastatic disease severity, ethical considerations, and palliative care treatment options. Thieme Medical Publishers 2018-10 2018-11-12 /pmc/articles/PMC6232044/ /pubmed/30425881 http://dx.doi.org/10.1055/s-0038-1675376 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited. |
spellingShingle | Francis, Antonia P. Chang, Michelle Dolin, Cara D. Chervenak, Judith Cardonick, Elyce Recurrent Cholangiocarcinoma in Pregnancy: A Case Report |
title | Recurrent Cholangiocarcinoma in Pregnancy: A Case Report |
title_full | Recurrent Cholangiocarcinoma in Pregnancy: A Case Report |
title_fullStr | Recurrent Cholangiocarcinoma in Pregnancy: A Case Report |
title_full_unstemmed | Recurrent Cholangiocarcinoma in Pregnancy: A Case Report |
title_short | Recurrent Cholangiocarcinoma in Pregnancy: A Case Report |
title_sort | recurrent cholangiocarcinoma in pregnancy: a case report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232044/ https://www.ncbi.nlm.nih.gov/pubmed/30425881 http://dx.doi.org/10.1055/s-0038-1675376 |
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