Cargando…

Prognostic and therapeutic significance of phosphorylated STAT3 and protein tyrosine phosphatase-6 in peripheral-T cell lymphoma

Peripheral T cell lymphomas (PTCL) is a heterogenous group of non-Hodgkin lymphoma and many patients remain refractory to the frontline therapy. Identifying new prognostic markers and treatment is an unmet need in PTCL. We analyzed phospho-STAT3 (pSTAT3) expression in a cohort of 169 PTCL tumors and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Han, Jing Jing, O’byrne, Megan, Stenson, Mary J., Maurer, Matthew J., Wellik, Linda E., Feldman, Andrew L., McPhail, Ellen D., Witzig, Thomas E., Gupta, Mamta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232096/ https://www.ncbi.nlm.nih.gov/pubmed/30420593 http://dx.doi.org/10.1038/s41408-018-0138-8

Ejemplares similares

JAK2 activation promotes tumorigenesis in ALK-negative anaplastic large cell lymphoma via regulating oncogenic STAT1-PVT1 lncRNA axis
por: Le, Kang, et al.
Publicado: (2021)

Translation initiation complex eIF4F is a therapeutic target for dual mTOR kinase inhibitors in non-Hodgkin lymphoma
por: Demosthenous, Christos, et al.
Publicado: (2015)

A Novel Missense (M206K) STAT3 Mutation in Diffuse Large B Cell Lymphoma Deregulates STAT3 Signaling
por: Hu, Guangzhen, et al.
Publicado: (2013)

Targetable fusions of the FRK tyrosine kinase in ALK-negative anaplastic large cell lymphoma
por: Hu, G, et al.
Publicado: (2017)

NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22
por: Spalinger, Marianne R., et al.
Publicado: (2023)

Protein Tyrosine Phosphatases as Potential Regulators of STAT3 Signaling
por: Kim, Mihwa, et al.
Publicado: (2018)

The effect of CRM1 inhibition on human non-Hodgkin lymphoma cells
por: Abeykoon, Jithma P., et al.
Publicado: (2019)

Inferior survival in high-grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements is not associated with MYC/IG gene rearrangements
por: McPhail, Ellen D., et al.
Publicado: (2018)

Loss of function mutations in PTPN6 promote STAT3 deregulation via JAK3 kinase in diffuse large B-cell lymphoma
por: Demosthenous, Christos, et al.
Publicado: (2015)

Tyrosine phosphorylation of a human killer inhibitory receptor recruits protein tyrosine phosphatase 1C
Publicado: (1996)

The tyrosine phosphatase PTPN13/FAP-1 links calpain-2, TBI and tau tyrosine phosphorylation
por: Wang, Yubin, et al.
Publicado: (2017)

Plasmablastic lymphoma with MYC::IGH fusion and BCL2 rearrangement
por: Barouqa, Mohammad, et al.
Publicado: (2022)

PSTPIP: A Tyrosine Phosphorylated Cleavage Furrow–associated Protein that Is a Substrate for a PEST Tyrosine Phosphatase
por: Spencer, Susan, et al.
Publicado: (1997)

Role of Protein Phosphorylation and Tyrosine Phosphatases in the Adrenal Regulation of Steroid Synthesis and Mitochondrial Function
por: Paz, Cristina, et al.
Publicado: (2016)

Regulation of the SNARE-interacting protein Munc18c tyrosine phosphorylation in adipocytes by protein-tyrosine phosphatase 1B
por: Bakke, Jesse, et al.
Publicado: (2013)

LptO (PG0027) Is Required for Lipid A 1-Phosphatase Activity in Porphyromonas gingivalis W50
por: Rangarajan, Minnie, et al.
Publicado: (2017)

T-Cell Protein Tyrosine Phosphatase Attenuates STAT3 and Insulin Signaling in the Liver to Regulate Gluconeogenesis
por: Fukushima, Atsushi, et al.
Publicado: (2010)

Response to interferons and antibacterial innate immunity in the absence of tyrosine‐phosphorylated STAT1
por: Majoros, Andrea, et al.
Publicado: (2016)

O-GlcNAcylation of STAT5 controls tyrosine phosphorylation and oncogenic transcription in STAT5-dependent malignancies
por: Freund, P, et al.
Publicado: (2017)

On the role of tyrosine phosphatases as negative regulators of STAT signaling in breast cancers: new findings and future perspectives
por: Tremblay, Michel L
Publicado: (2013)

Induction of tyrosine phosphorylation during ICAM-3 and LFA-1-mediated intercellular adhesion, and its regulation by the CD45 tyrosine phosphatase
Publicado: (1994)

Protein tyrosine phosphatase-1B regulates the tyrosine phosphorylation of the adapter Grb2-associated binder 1 (Gab1) in the retina
por: Rajala, Ammaji, et al.
Publicado: (2013)

Phosphorylation inhibition of protein-tyrosine phosphatase 1B tyrosine-152 induces bone regeneration coupled with angiogenesis for bone tissue engineering
por: Tang, Yong, et al.
Publicado: (2021)

High rate of event-free survival at 24 months with everolimus/RCHOP for untreated diffuse large B-cell lymphoma: updated results from NCCTG N1085 (Alliance)
por: Witzig, T E, et al.
Publicado: (2017)

Whole-exome analysis reveals novel somatic genomic alterations associated with outcome in immunochemotherapy-treated diffuse large B-cell lymphoma
por: Novak, A J, et al.
Publicado: (2015)

RPTPμ tyrosine phosphatase promotes adipogenic differentiation via modulation of p120 catenin phosphorylation
por: Kim, Won Kon, et al.
Publicado: (2011)

Tuning the Protein Phosphorylation by Receptor Type Protein Tyrosine Phosphatase Epsilon (PTPRE) in Normal and Cancer Cells
por: Liang, Jinping, et al.
Publicado: (2019)

Off-target effects of protein tyrosine phosphatase inhibitors on oncostatin M-treated human epidermal keratinocytes: the phosphatase targeting STAT1 remains unknown
por: Hong, Brian V., et al.
Publicado: (2020)

Tyrosine phosphorylation and bacterial virulence
por: Whitmore, Sarah E, et al.
Publicado: (2012)

Protein tyrosine phosphatase receptor type delta (PTPRD) suppresses the expression of PD-L1 in human hepatocellular carcinoma by down-regulating STAT3
por: Meng, Qiuhua, et al.
Publicado: (2020)

The tyrosine kinase c-Abl potentiates interferon-mediated antiviral immunity by STAT1 phosphorylation
por: Liu, Hainan, et al.
Publicado: (2021)

Opposing Effects of Chelidonine on Tyrosine and Serine Phosphorylation of STAT3 in Human Uveal Melanoma Cells
por: Csomós, István, et al.
Publicado: (2021)

Roles of protein tyrosine phosphatases in hepatocellular carcinoma progression (Review)
por: Chen, Yi-Li, et al.
Publicado: (2023)

Protein tyrosine phosphatases in glioma biology
por: Navis, Anna C., et al.
Publicado: (2009)

Metabolic regulation by protein tyrosine phosphatases
por: Knobler, Hilla, et al.
Publicado: (2014)

Role of Protein Tyrosine Phosphatases in Plants
por: Shankar, Alka, et al.
Publicado: (2015)

Crystal structure of the Yersinia tyrosine phosphatase
por: Bliska, James B.
Publicado: (1995)

T Cell Protein Tyrosine Phosphatase in Osteoimmunology
por: Wang, Ya-nan, et al.
Publicado: (2021)

Protein tyrosine phosphatases in cell adhesion
por: Young, Katherine A., et al.
Publicado: (2021)

Protein Tyrosine Phosphatases: Mechanisms in Cancer
por: Sivaganesh, Vignesh, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_eva4hcknicks071lgemh5mqoo8