REX1 is the critical target of RNF12 in imprinted X chromosome inactivation in mice

In mice, imprinted X chromosome inactivation (iXCI) of the paternal X in the pre-implantation embryo and extraembryonic tissues is followed by X reactivation in the inner cell mass (ICM) of the blastocyst to facilitate initiation of random XCI (rXCI) in all embryonic tissues. RNF12 is an E3 ubiquiti...

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Detalles Bibliográficos
Autores principales: Gontan, Cristina, Mira-Bontenbal, Hegias, Magaraki, Aristea, Dupont, Catherine, Barakat, Tahsin Stefan, Rentmeester, Eveline, Demmers, Jeroen, Gribnau, Joost
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232137/
https://www.ncbi.nlm.nih.gov/pubmed/30420655
http://dx.doi.org/10.1038/s41467-018-07060-w

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