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Diverse Protein Profiles in CNS Myeloid Cells and CNS Tissue From Lipopolysaccharide- and Vehicle-Injected APP(SWE)/PS1(ΔE9) Transgenic Mice Implicate Cathepsin Z in Alzheimer’s Disease
Neuroinflammation, characterized by chronic activation of the myeloid-derived microglia, is a hallmark of Alzheimer’s disease (AD). Systemic inflammation, typically resulting from infection, has been linked to the progression of AD due to exacerbation of the chronic microglial reaction. However, the...
Autores principales: | Thygesen, Camilla, Ilkjær, Laura, Kempf, Stefan J., Hemdrup, Anne Louise, von Linstow, Christian Ulrich, Babcock, Alicia A., Darvesh, Sultan, Larsen, Martin R., Finsen, Bente |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232379/ https://www.ncbi.nlm.nih.gov/pubmed/30459560 http://dx.doi.org/10.3389/fncel.2018.00397 |
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