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Inhibition of Heat Shock Protein 90 by 17-AAG Reduces Inflammation via P2X7 Receptor/NLRP3 Inflammasome Pathway and Increases Neurogenesis After Subarachnoid Hemorrhage in Mice

Subarachnoid hemorrhage (SAH) is a life-threatening cerebrovascular disease that usually has a poor prognosis. Heat shock proteins (HSPs) have been implicated in the mechanisms of SAH-associated damage, including increased inflammation and reduced neurogenesis. The aim of this study was to investiga...

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Detalles Bibliográficos
Autores principales:	Zuo, Yuchun, Wang, Jikai, Liao, Fan, Yan, Xiaoxin, Li, Jianming, Huang, Lei, Liu, Fei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232389/ https://www.ncbi.nlm.nih.gov/pubmed/30459553 http://dx.doi.org/10.3389/fnmol.2018.00401

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