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Elevated Glutamate and Glutamine Levels in the Cerebrospinal Fluid of Patients With Probable Alzheimer's Disease and Depression

Recent evidence suggests that Alzheimer's disease (AD) and depression share common mechanisms of pathogenesis. In particular, deregulation of glutamate-mediated excitatory signaling may play a role in brain dysfunction in both AD and depression. We have investigated levels of glutamate and its...

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Detalles Bibliográficos
Autores principales: Madeira, Caroline, Vargas-Lopes, Charles, Brandão, Carlos Otávio, Reis, Taylor, Laks, Jerson, Panizzutti, Rogerio, Ferreira, Sergio T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232456/
https://www.ncbi.nlm.nih.gov/pubmed/30459657
http://dx.doi.org/10.3389/fpsyt.2018.00561