Recombinant Infectious Bronchitis Viruses Expressing Chimeric Spike Glycoproteins Induce Partial Protective Immunity against Homologous Challenge despite Limited Replication In Vivo

Vaccination regimes against Infectious bronchitis virus (IBV), which are based on a single virus serotype, often induce insufficient levels of cross-protection against serotypes and two or more antigenically diverse vaccines are used in attempt to provide broader protection. Amino acid differences i...

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Detalles Bibliográficos
Autores principales: Ellis, Samantha, Keep, Sarah, Britton, Paul, de Wit, Sjaak, Bickerton, Erica, Vervelde, Lonneke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Vaccines and Antiviral Agents
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232476/
https://www.ncbi.nlm.nih.gov/pubmed/30209177
http://dx.doi.org/10.1128/JVI.01473-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232476/
https://www.ncbi.nlm.nih.gov/pubmed/30209177
http://dx.doi.org/10.1128/JVI.01473-18

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