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Recombinant Infectious Bronchitis Viruses Expressing Chimeric Spike Glycoproteins Induce Partial Protective Immunity against Homologous Challenge despite Limited Replication In Vivo
Vaccination regimes against Infectious bronchitis virus (IBV), which are based on a single virus serotype, often induce insufficient levels of cross-protection against serotypes and two or more antigenically diverse vaccines are used in attempt to provide broader protection. Amino acid differences i...
Autores principales: | Ellis, Samantha, Keep, Sarah, Britton, Paul, de Wit, Sjaak, Bickerton, Erica, Vervelde, Lonneke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232476/ https://www.ncbi.nlm.nih.gov/pubmed/30209177 http://dx.doi.org/10.1128/JVI.01473-18 |
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